EVALUATION OF ANTIMICROBIAL POTENTIAL OF FRUIT PEEL AND PLANT SEEDS AGAINST MULTIDRUG-RESISTANT STAPHYLOCOCCUS AUREUS

Author (s) : Dr.A.Sumithra

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Abstract :
Multidrug-resistant Staphylococcus aureus (MDR-SA) poses a significant threat to public health, leading to increased morbidity and mortality worldwide. As conventional antibiotics continue to lose efficacy against this formidable pathogen, alternative strategies are urgently needed. This study aimed to investigate the antimicrobial potential of fruit peel and plant seeds extracts against MDR-SA strains.   The experiment involved the collection and extraction of bioactive compounds from the peels of select fruits and seeds of specific plant species. The fruit peel extracts were derived from citrus fruits (e.g., oranges, lemons) and plant seeds were sourced from seeds (e.g., grape seeds, avocado seeds). The extraction process involved various solvents to obtain a range of compounds with potential antimicrobial properties. Further analysis identified specific bioactive compounds in the fruit peel and plant seed extracts, such as flavonoids, phenolic acids, and essential oils, known for their antimicrobial properties. These compounds likely contributed to the observed antimicrobial activity against MDR-SA strains.   In conclusion, this study highlights the promising antimicrobial potential of fruit peel and plant seed extracts against multidrug-resistant Staphylococcus aureus. The identification of active compounds may pave the way for the development of novel antimicrobial agents or adjuvants to combat MDR-SA infections. However, further research is warranted to elucidate the underlying mechanisms of action and assess the safety and efficacy of these natural extracts in vivo. Embracing alternative sources of antimicrobial agents could hold promise for tackling the growing threat of antibiotic resistance.

Keywords : Multidrug-resistant, Staphylococcus aureus, Bioactive

Conference Date : 13/11/2020

Pages : 317

Paper ID : 20317