BIO-DETERIORATION OF COSMETICS AND PHARMACEUTICAL PRODUCTS

Author (s) : Dr.M.Ambiga ,K.Hamsa & T.Devi,D.Jeevithra

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Abstract :
Cosmetics are being manufactured in the form of lotions, creams, liquids, solids and powder forms. Some are stickers and used externally for cleaning and decorative purposes. They consist of large quantity of water, animal, plant/mineral oils, natural gums thickening agents, carbohydrates, aroma and flavouring agents in addition to protein hydro lysates, milk, beer, egg, plant extracts, etc. These product formulations are good sources of nutrients for microbes. Several species of micro-organisms produce toxic molecules and may render a product dangerous if they grow in it under conditions supporting toxin production. Various disinfectants contain ammonia compounds, reported to be contaminated with pseudomonades, for example Pseudomonas aeruginosa contaminates eye drops, washes and mascara, etc. Some injectables contain Gram-negative bacteria, fungi, etc. which produced endotoxins (pyrogens) that directly induce fever.Microbial quality control is a necessary step to check the deterioration of crude and finished materials. It is conducted to monitor microbial contamination of raw materials, to monitor and confirm the efficacy of operations such as sterilization, to control the pathogenic microorganisms (by their absence), and to evaluate the expected storage period.

Keywords : water, animal, plant/mineral oils, Pseudomonas aeruginosa, endotoxins

Conference Date : 30/08/2019

Pages : 350

Paper ID : 19341