STUDY ON L-ASPARAGINASE ENZYME PRODUCED BY STREPTOMYVCES SP ISOLATED FROM WESTERNGHATS

Author (s) : R.Selvabharthi, S.Chandralekha, & D.Jeevithra, A.Mohanapriya

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Abstract :
L-Asparaginase is an enzyme that is used as a medication and in food industry. It has been proved to be efficient in treatment of Acute lymphoblastic leukemia and Lymphosarcomas. The use of L-Asparaginase in food industries is to reduce acrylamide levels in cooked food. Microbial fermentation is an alternative source for production of L-Asparaginase enzyme due to its low cost, easy culturing techniques as well as efficient purification. The aim of the present study is to screen Actinomycetes possessing extracellular L-Asparaginase production capacity. In addition, optimization of cultural and environmental conditions required for enzyme production will be carried out for the highest L-Asparaginase producer in submerged and solid state fermentation.

Keywords : L-Asparaginase, Acute Lymphoblastic Leukemia, Actinomycetes, Fermentation, Optimization.

Conference Date : 17/09/2021

Pages : 271

Paper ID : IESMDT269