SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL STUDIES OF A CHIRAL COMPOUND AND ITS METAL COMPLEXES

Author (s) : D.Saravanan, D.Kodimunthiri, R.Menaga& R.Elamparithi

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Abstract :
A chiral Mannich base, [1-(piperidin-1-yl (thiophen-2-yl) methyl)] thiourea (TPPTU) was prepared by treating thiophene-2-carbaldehyde piperidine and thiourea. Using TPPTU as a ligand, metal complexes of Mn (II), Co (II), Ni (II), Cu(II) and Zn(II) were prepared. Both the compound and complexes were characterized by physical methods such as elemental analysis, melting point and TLC and spectral methods such as IR, UV –Visible, 1H NMR, 13C NMR and Mass spectral studies. For the complexes, molar conductivity, magnetic susceptibility and thermal studies were also been carried out. In vitro antimicrobial study was carried out for both the compound and complexes.

Keywords : Mannich base complexes, Thiopene-2-aldehyde, Piperdine, Antimicrobial studies

Conference Date : 17/09/2021

Pages : 201

Paper ID : IESMDT199