ANTIMICROBIAL ACTIVITY OF LIQUID MICROBIAL CONSORTIUM: A COMPREHENSIVE REVIEW

Author (s) : Dr.R.Thilagam,

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Abstract :
The emergence of antimicrobial resistance in various pathogenic microorganisms has become a pressing global health concern. As conventional antibiotics lose their efficacy, alternative strategies are urgently required to combat infectious diseases. The liquid microbial consortium (LMC) has garnered significant attention as a promising antimicrobial agent due to its potential to counteract resistance mechanisms and promote sustainable disease management. This review aims to provide a comprehensive overview of the current state of research on the antimicrobial activity of LMC. The LMC is a diverse community of microorganisms, including bacteria, fungi, and other microbial entities, that interact synergistically to produce a broad spectrum of antimicrobial compounds. This dynamic consortium exhibits unique properties that make it an appealing candidate for combating infections. The antimicrobial action of LMC involves the production of secondary metabolites, such as antimicrobial peptides, enzymes, organic acids, and volatile organic compounds. These metabolites exhibit inhibitory effects against a wide range of pathogens, including bacteria, viruses, fungi, and protozoa. Moreover, LMCs have shown promise in combating biofilm formation, which is notoriously challenging to treat with conventional antibiotics. Several studies have evaluated the antimicrobial potential of LMCs against various pathogens, both in vitro and in vivo. The findings indicate that LMCs demonstrate considerable effectiveness in inhibiting pathogenic growth and biofilm formation. Furthermore, this review explores the factors influencing the antimicrobial activity of LMCs, including the composition and diversity of the consortium, environmental factors, and cultivation methods. Additionally, the safety and potential side effects of LMC application in different settings are discussed.  Overall, the antimicrobial activity of liquid microbial consortia presents a promising avenue for the development of novel antimicrobial agents to combat infectious diseases. Further research is warranted to better understand the complex interactions within LMCs, optimize their production, and evaluate their efficacy in clinical settings. The successful harnessing of LMCs as an antimicrobial agent could potentially revolutionize the field of infectious disease management and provide a sustainable solution to the global antimicrobial resistance crisis.

Keywords : Liquid microbial consortium, Antimicrobial Activity

Conference Date : 17/09/2021

Pages : 115

Paper ID : IESMDT113